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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df15ff4de9e4595077ba90b55a3a7edeeb6d263ec4f26b7e1722046bc7d39bc5' 
  AND token = 'Zw9GwOU6zeCENMYckOehKS7on7zkgcl32gjIXjPZKRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}