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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1c6e9f226aa74a43f7af840c024abc5c5dd476ea3148ecfba256c0811ae71a' 
  AND token = 'eMqgupSSeWLpBFdXeFfQQ6YX0SX1cP8lBdBc04f+5f0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}