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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324ce649fb0f61180f23a052e10ad373ab2f4b2c7de61ecb31723e0134c1e840' 
  AND token = 'htsiVIB4FU5fOuyOT+rrJg7ApN9s8PUF1SBGprHDX9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}