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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb94671e1eb506591dca1910f8f6305e9b66be34ea021e30cbbc2b57df57d99' 
  AND token = 'yG4soCI6AgS0YGhaWFuhL7gWsImOTeW5TsqfLWlb9ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}