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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d505b1b58c6c3a4923f75578e2b9d4bbad1be87851ed837c64663cdef8034d3' 
  AND token = 'MTVips3bIwmZ4CMZ4JV152psYRDNk5Q+qNj5eN+FzZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}