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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014e64419fc74de8e253e4807d4347e04028a585116d28e1387b2594171d1e9b' 
  AND token = '1BaoieR+r3FgYCKfXwxrkAaIz35lKNp1v7Ks4ODxUmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}