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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad3a5067180ecc1149b755f6bced8d8b3c6c0ef4de56b2989f336123b4b90101' 
  AND token = 'wxf3RgOqHeb5y8CEDSZYPw1CdDn7YD61mIGD/j8qFCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}