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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961c84287f318e0b49461ea3b2bdf8f3f8829e3c58890bc25263e1be0e013d6f' 
  AND token = '8vJkTyX/JnO3yTcoWWNb7Zc3fsaCtaM3Cw02CpUoXIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}