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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1986dcfc077a68afece0b5ca8b1d7a6375a63c8934a3519b109c6184cf932d' 
  AND token = 'GCwdCEp6vYDODKkVJWPE+TE2akwz622pxheWjweVxrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}