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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5fe22991bb340af3b348018b6591e993512d33a97f0ba7da50a6623bf252e3c' 
  AND token = 'L/frXSl4N2NjocuU4DO6YsQk7cEj2uNJ0USJ4Ar61EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}