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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8d5c37f9bc6bed4517f378df685621dc6c2bd9b5a0718bbf89805c8186abf1' 
  AND token = 'a2IlgcCOtccV41ioAd8cWf8pk+AOYB7jYZdBJ+QSPfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}