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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9909c98cf5c353b5604e50f85d8b5bf6e723d1717f58a0fb8a2622dc4f2dcd7' 
  AND token = 'CP66tPGIua+QxWjHWPuqllhLJpNi9sFjUg5Q2SWWTuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}