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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8cf660ad3962753e4d3236c6e7a07c63ebe0fbb86d899cdbd5e1e7355d4bba' 
  AND token = 'RYjia06Nsql1IbeGJtQ0n9WqudS/gQV5gQDFg7/OzUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}