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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c2614c25fe1a440de1639084fa4ec039b7d6526dd5171bb659d3aa92949a9d' 
  AND token = 'Mx89iOIAAxfE1BqApxIiFrMTCBKoZWSLs/6fS4kfsvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}