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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a5f432d54145eb371c950f1c2f9d9c5563bdab17e5022f1571a2d462a179afd' 
  AND token = '5qi14e+5jPfWAfTpIK2HA9kVBJg5xSxqn6EHAizwH4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}