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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5610d5d9c392a3df5b756b7cdde84d926ec29b6bd5de98df0014933a75dfe3c2' 
  AND token = 'YmcMRVs/SC405szqmdhwaAkCzqaocAEKnKWZzp2e7FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}