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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4020764ab8c5d6cf92fe7bcc05a825066db6e1552a832ba0bd95442922134cb4' 
  AND token = 'Wi32jR7TTg2zcAoErz8a1tosunaUw4Wglei6inx9AV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}