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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dae48b82d9dd3b8e9e04b72f48c4ba3c7b379e8b0018b34a9a15fdcaa554098b' 
  AND token = 's4avBPZGUgiYR1r/7sQK+j8oORatOWHqO9xQLSEHDAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}