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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce976ebea4dc225b12bb026be6f7b733a4dba972001062b85f6aac04c5f16d0' 
  AND token = '5u8QxW7OVyY2UYlyK/BZCLGQsieihMc6Y8lNvvcueiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}