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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785caefeb83bf30540cfa7f0f37b3a1da8f2b29bc4e2c1251da54a648da8cb79' 
  AND token = '0TGMDk+czkagmTuyjx4gs4lnkZJ6Yviu5yeuJBiNnrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}