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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a7c7e07180e67b05260ded2f2e6057fc9775de621d5662c9607299e3fa803e' 
  AND token = 'Zsd2KBXqZusHNTsrfELHccxbgqSP3hCnVD/LyEt38qA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}