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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea98875ab12ab833bccb3d17a4db1067f5f160680d9973be6cce940ea017847' 
  AND token = 'UI8S9UYHh0SmWeG+nTRoQzAey4ITb4OlFlyIU8ZEGJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}