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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bfa6976da4700957604c6bbf4631c004bae05b7631c01e7dd726a3f995e8b1f' 
  AND token = 'ce/VeXD3u8qePB5yPn3bzAXzH5x+jHTbVh7wXIBBHGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}