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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452925f21bdf18840415deb879942937908622158a89ec488bc78b3c16ee9019' 
  AND token = 'JjXlkh9vOK2Br6cmc4YvcJKDdsiyfG54yS0C6rqfgZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}