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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a39d2741da8280346b5e0f89417500f56d93b992ee53249a27c4b5d23c972c39' 
  AND token = 'pUDXzUzC1fuEse/L6k1pZn0QZMPzqQzr6KO/G27+O2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}