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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8e823250ffbed1a61d6c0f44aed74367ff7c69ef64956757dba766ed8f1f1c' 
  AND token = 'Fz3coBx1GZzxlRh3mwp6Z3hfrr5zgUamLeVVItPVzWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}