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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e95fd2a901f12a81a32c636cb91d828b0663a237680f9561c0c160c93174b7a' 
  AND token = '7cr7UFDvmlNZIxAnQDbonZXyuTaC1ZEWwHrt/api8nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}