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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3558b114b31987f60a871e1bc144e5df0f94f70c9ba0f83baa238646fc37908c' 
  AND token = 'ywp+GqMXVzXO4cWS3x/6AT+S/71wt0Fis/UEBi142P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}