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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4230ee6d2f1f2f9a4e44d325c644a5019e315eb79505277c0cc2151a24f17579' 
  AND token = 'eM83/NWlrO310uZ6Jlvm/FhzbG65ea7B0ISUrQg5mIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}