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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '210e71d0e08e911aaeefc4d0b46d11385a10dc1847c9a194166e7b4a7fd98b0b' 
  AND token = 'EGtN90N1yiTDtE8/ldqQMuZAQixLfn2/6ZvV2Wk4kdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}