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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db85b16b1e2061d5e49afe917a3c1016a4dd05d76fbfe5d84bbe0a8b5116e176' 
  AND token = 'aBiDtMDO7jP6xEAwp6uFgZkV6t01TlASx0wwcHUK66Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}