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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4770730356d1c853d9082abcdddae4c42bd8a0140dc6861a2d45c8453fe39203' 
  AND token = 'AkD1cYdxAsDiwNQtXmi4tXzmmVys0x2OgbO/06SHmgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}