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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9270f98121a32bec3e2c645f1194e085221601c344fbcb3c31c0c22ba49c114a' 
  AND token = 'P9od8RD+YXIy6/bJbVS97xp2TGQXlhwuLfLSN1jJ17c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}