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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f072f7efe9e6cb0693a119a29132f8eee9668896bc2ad212f131e563d0c190' 
  AND token = 'IY7X3MbqjLvjCwFysTT9peLDHUYk480a4AjwTm+4PE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}