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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2292cdfab20e3c9c79684111d9bcc9cfa4e8a5d42cf0d5274707c350b5f9859' 
  AND token = 'FcNIs/sjupJ6ajDapaN7N/Ot5NFCeKGCv8SYxZoBHJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}