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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df2b14ef7f5c9d1232c5d09611808123fa951893db42e57f05cb95e255217d0' 
  AND token = '6k7AJNh+XhThSpkP0GrVWjzGi6OI1z29LoBCsiCwrx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}