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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11945202e86372d714368f173083291636354b0e7c42351fdccfd4b50441c76a' 
  AND token = '3oG3R3/GW9+JtgR15erIOObCQmS48c7q8P+LjHKKowg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}