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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fd9256609a6514f7d1ec0e3720a2b5da0929fb5fb0c57017711d3c30f8c627' 
  AND token = 'By2z3gneC3Gw4GaD1V6Ca93bNb9XNPf8GDW4whS6LBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}