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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35e8bfaed09a4860505b54d49e2b239c14377fd59f87bc431440b01bade9bff' 
  AND token = '0gvEzdvMBE8gUexfR+vhcW30sdJGBRN1fh06rzy91Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}