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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787a64f428324145e2cc28e46f8e7f669f98dc10c11036c8f3a9e80ba3e30a97' 
  AND token = '1dNUyVVe/WbXoKw+YkDdwLVDVm3JXlvBZ4aowHHVl18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}