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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490e2b81c0670c05dfc30523bfc6b5b3ef9da1f5a59480acea3d2047358d64a4' 
  AND token = 'Cnlxm0LEa7vQ7gnY7UTfp0QeD7GkO59w5EKhSq3BEEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}