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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21485eac2120a9bd8852229c6ebb8f2d209c52048e7040639357caeab94170b5' 
  AND token = 'H43LvT+HPG2k0q0wLoY+q+4+QStEA54aWacwR15jmXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}