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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4639718554248da51bd248032988bab4f06174fef27f93980fdb3786b1f632' 
  AND token = 'CVYGyS9D7bCCEF+Kpy0CEJCXNDKSGf7WYdHZZsFQM9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}