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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1458075118fc946b8f6a6ee305793ed6492466044e5c7babad5b163c889a49e4' 
  AND token = 'v9cL48M9Z7Ri1t6dK+ZbAJ8jX8pwe22GyDGtn/1kWdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}