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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ede8a0210dba93cdc849147e12e6cdbe85eeea0bc72063e31c001a63c929171' 
  AND token = 'WLcha3KUtG71QhX0DnZ50dNyvB/35DEtG6AIqFwlXGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}