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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb57d60c4f1a9d6bcb314ba64a3eace4f28f4c158f8e6e8e251a1dee7eef3af2' 
  AND token = 'lGQc4cR8nAD4iu7LBQt9Kw0LXZ4JsapdGW9E+vj7oQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}