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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c4dc4dcbb02425d762c00aeb02f36ff94845c186181dbf6317d3435e7ac8f1' 
  AND token = 'SqPeF5/qayJV26ASFOgzsRQZ/Rb/jREaVjfcbvC0+yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}