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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aecf9c1201831a616cf3f01f1c59d6708856cbca2449199bb852483a986cd9cc' 
  AND token = 'yk4/SARlyOeR+dCiI5RUoIY09xzWcAF+33f4u5z7Bj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}