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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f9239b4331c69e75be08a4f214d183d9f52ca25ce0afa332ec305014670c00' 
  AND token = 'bbKRmdybVD9WiACdNjEUHxs8e018fEYVzOqlql232gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}