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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605ffeef69137024aef0f2ac84eafe4378b82b40497da3eb0d46e54d570d1b74' 
  AND token = 't2UZmBH0wNJBkYgrdWOqJDzoA6MfQxh3FoTA+QIsTtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}